A research team has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule. The breakthrough reveals how ...

The structure of a large nucleic acid complex formed by the 10–23 DNA enzyme bound to an RNA substrate was determined by X–ray diffraction at 3.0 Å resolution. The 82–nucleotide complex contains two ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

Current demand for plastics and chemical raw materials is met through large-scale production of ethylene from fossil fuels.

The γ-secretase enzyme can cleave more than 150 membrane proteins. These include the amyloid precursor protein, which produces deposits linked to Alzheimer’s disease, and the Notch1 protein, which is ...