Chemists are taking a p[h]age from bacteria's playbook in order to beat viruses at their own game and develop new drugs to fight cancer and a host of other human diseases in the process. Chemists at ...
Reviewed by Michael Greenwood, M.Sc. In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug ...
With a phage-display library derived from prostate-cancer tissue, we developed and used phage protein microarrays to analyze serum samples from 119 patients with prostate cancer and 138 controls, with ...
Recent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gaps and limitations associated with next generation sequencing ...
A revolutionary new antivenom has proven effective against snakebites from 17 of the world’s deadliest serpents. Scientists ...
The 2018 Nobel Prize in Chemistry was awarded to Frances H. Arnold and the other half jointly to George P. Smith and Sir Gregory P. Winter on Wednesday for their work harnessing the power of evolution ...
Company will combine this technology with ribosome display to increase speed and reliability of screening. Scil Proteins acquired a phage-display technology known as Tat Phage display from the German ...
From L to R: Frances H. Arnold was recognized for her work in the directed evolution of enzymes, while George P. Smith and Sir Gregory Winter were honored for the phage display of peptides and ...
Techniques that put natural evolution on fast-forward to build new proteins in the lab have earned three scientists this year’s Nobel Prize in chemistry. Frances Arnold of Caltech won for her method ...
mRNA display is a technique that can identify proteins which bind to specific regions in DNA. This method has several advantages over other methods, such as yeast-to-hybrid, immunoprecipitation, phage ...