The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking ...
Approach that uses cell’s own strategy of liquid-liquid phase separation protects synthetic modifications from being washed away by the tide of cell growth.
News Medical on MSN
New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression
Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for ...
Epitranscriptomics, the study of dynamic co- or post-transcriptional modifications on RNA, has emerged as a vibrant field in neurobiology. Major advances in ...
In the Alzheimer’s brain, microglia diversify into several activation states. What controls this specialization? In a preprint posted to bioRxiv on October 13, scientists led by Martin Kampmann at the ...
Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...
This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...
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